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IMPOTENCE – TRIAL DRUGS

Only when the trial has been completed is the key broken and it is disclosed which patients have been given the drug and which the placebo. The purpose of a double blind trial of a drug is to reduce the bias from psychological influences, and to try objectively to evaluate the value of a drug. Psychological influences are so significant that they must be excluded. An example of their influence is shown by the experience of a group of women who were all taking the pill. A number complained of side-effects of such magnitude that they wished to change the brand of pill they were taking. They were granted their wish and given a brand of pill which was beautifully packaged. Immediately most of the unpleasant side-effects disappeared. It was obvious to the women that the new pill was better than the old one. Unfortunately, there was a flaw in their feeling. The new pill was identical in chemical composition with the old one – only the name and the package were different.

Few investigations using a double blind trial have been made in treating impotence by using male hormones, and of those which have, most have shown no significant improvement’ among impotent men given testosterone, unless the impotence was due to disease.

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